Internal Seminar: Anti-angiogenetic, neuroprotective and cytotoxicity study of anti-angiogenetic, neuroprotective and cytotoxicity study of Blechnum spicant
Mrs. Sawsan Assistant Lecturer in the Biology Education Department, Faculty of Education at Tishk International University, recently hosted an internal seminar that focused on exploring the therapeutic potential of natural plant extracts in the context of neurodegeneration and angiogenesis. The seminar aimed to shed light on the intricate relationship between these processes and how plant extracts could be leveraged for potential therapeutic interventions.
Mrs. Sawsan emphasized the complex interplay between neurodegeneration and angiogenesis. Neurodegeneration involves the gradual deterioration of neurons function, while angiogenesis pertains to the formation of new blood vessels. Dysfunctional angiogenesis can exacerbate neurodegenerative processes by compromising blood flow and nutrient delivery. The presentation also touched upon ocular angiogenesis (neovascularization), a significant concern in vision-related disorders. The development of new blood vessels in the retina and cornea can lead to vision impairment due to vessel leakage.
Mrs. Sawsan presented findings from recent research conducted in her lab. The study investigated the neuroprotective, antiangiogenic, and cytotoxic properties of Blechnum spicant extracts obtained using various solvents, including water, methanol, dichloromethane, and hexane. Notably, the water extract displayed remarkable neuroprotective and antiangiogenic activity. This effect was attributed to the water extract’s ability to extract potent antioxidant compounds, particularly effective in polar solvents.
The seminar provided valuable insights into the potential therapeutic applications of natural plant extracts in the fields of neurodegeneration and angiogenesis. Her research findings underline the significance of exploring these plant extracts for future therapeutic interventions.
