TISHK INTERNATIONAL UNIVERSITY
FACULTY OF EDUCATION
Department of BIOLOGY EDUCATION,
2022-2023 Fall
Course Information for BIO 305 MOLECULAR BIOLOGY
Course Name: MOLECULAR BIOLOGY
Code Regular Semester Theoretical Practical Credits ECTS
BIO 305 5 3 – 3 4
Name of Lecturer(s): Harmand Ali
Teaching Assistant: Harmand Al. Hama
Course Language: English
Course Type: Main
Office Hours Sun. 13:30-15:30
Contact Email: [email protected]

Tel:07501917303
Teacher’s academic profile: BSc. in Biology Science MSc. in Molecular Biology
Course Objectives: At the end of this module, student will be able to: • Review critically the fundamental and key concept of Molecular biology and genetics background. • This course is about genes – their structure and function – therefore, students will study nucleic acid structure and the mechanics of replication, repair, transcription, and translation. • A central goal is understanding gene regulation at all levels, and the structure-function relationships of nucleic acids and proteins. Critical experiments will be examined to learn how our current understandings have come about. • Techniques in molecular biology will be examined in lecture as necessary to understand experiments and concepts. We will also study protein structure and function – especially protein interactions with nucleic acids – and post-translational events since proteins constitute the functional output of genes (with an increasing number of exceptions).
Course Description (Course overview): This course Provide a strong background in the cellular and molecular aspects of biology with particular emphasis on eukaryotes. This course deals with nucleic acids and proteins and how these molecules interact within the cell to promote proper growth, division, and development. It is a large and ever-changing discipline. This course will emphasize the molecular mechanisms of DNA replication, repair, transcription, splicing, protein synthesis, and gene regulation in different organisms. This course takes an in-depth look at some rapidly evolving fields, including chromatin structure and function, genome editing techniques, back splicing, and regulation of gene expression by different types of RNAs.
COURSE CONTENT

Week Hour               Date Topic
1 2 2-6/10/2022 Syllabus introduction and basic concept of Molecular Biology
2 2 9-13/10/2022 Definition of molecular biology, DNA as genetic material, Griffith experiment
3 2 16-20/10/2022 Genome, Origin of term, Overview, Types, Comparison of different genome type, Nucleic acid structure and function.
4 2 23-27/10/2022 DNA Binding Proteins
5 2 30/10-3/11/2022 FLOW OF GENETIC INFORMATION AND CENTRAL DOGMA OF MOLECULAR BIOLOGY
6 2 6-10/11/2022 DNA REPLICATION
7 2 13-17/11/2022 Midterm Exam
8 2 20-24/11/2022 RNA TRANSCRIPTION
9 2 27/11-1/12/2022 Post transcriptional modifications
10 2 4-8/12/2022 RNA TRANSLATION (PROTEIN THENSYSIS)
11 2 11-15/12/2022 Post Translational Modification
12 2 18-22/12/2022 DNA Mutation & DNA Repair mechanism
13 2 25-29/12/2022 Molecular biology Of Cancer
14 2 1-5/1/2023 MOLECULARE TECHNIQUES
15 2 8-12/1/2023 Final Exam
16 2 15-19/1/2023 Final Exam
COURSE/STUDENT LEARNING OUTCOMES

1 After completion of this course, the students will be able to define molecular biology. With a good background to explain the molecular concepts
2 Student will be familiar with the molecular process which are happening inside the cells including DNA replication, RNA transcription, and protein synthesis in different organisms.
3 Understanding about the main enzymes and their rules in DNA replication, RNA transcription, and protein synthesis process in both prokaryotic and eukaryotic cells will be another outcome for the students.
4 Students will be familiar about the idea of functional RNA preparation process (post transcriptional process) in eukaryotic cells.
5 Student will know about DNA mutation process and it’s repairing mechanisms. Moreover, understanding about both classical and modern molecular techniques.
COURSE’S CONTRIBUTION TO PROGRAM OUTCOMES
(Blank : no contribution, I: Introduction, P: Profecient, A: Advanced )

Program Learning Outcomes Cont.
1 Write accurately and clearly about biology topics that conform to the scientific conventions of that field. I
2 Describe the molecular components of living things, their heredity transformations and the main concerns in these biological process A
3 Identify and analyze the microorganisms including bacteria, fungi and virus and their roles in nature. P
4 Characterize the features of plant organs/tissues/cells/organelles involved in cellular respiration, photosynthesis, reproduction and growth. I
5 Describe the micro and macro anatomy of the living systems and recognize the relationship between structure and function at all biological systems and levels. P
6 Apply safety and proper techniques in the laboratory, and report the results of conducted experiments. P
7 Use appropriate methods and techniques to improve their students’ critical thinking, creative thinking and problem-solving skills. P
8 Effectively organize and manage classrooms.
9 Use required methods and techniques for student-centered teaching by considering individual and cultural differences of students.
10 Develop research studies that applies quantitative or qualitative research methods that address research questions in the field. P
Prerequisites (Course Reading List and References): 1.Biochemistry module, Cell Biology module, Biophysics module. 2. Reece, J. B., Urry, L. A., Cain, M. L., Wasserman, S. A., Minorsky, P. V., & Jackson, R. B. (2014). Campbell biology (No. s 1309). Boston: Pearson.
Student’s obligation (Special Requirements): Textbook Course Book Class attendance at every session, and full participation Satisfactory completion of two examinations the Mid-Term and Final Exam, and quizzes. Following and performing assignments on time.
Course Book/Textbook: 1.Cox, M. M., Doudna, J. A., & O’Donnell, M. (2012). Molecular biology: principles and practice (p. 809). New York, NY. USA:: WH Freeman and Company. 2.Lodish, H., Berk, A., Kaiser, C. A., Krieger, M., Scott, M. P., Bretscher, A., … & Matsudaira, P. (2008). Molecular cell biology. Macmillan. 3. Davis, L. (2012). Basic methods in molecular biology. Elsevier. 4. Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. cell, 144(5), 646-674.
Other Course Materials/References: Lecture’s note, PowerPoint, and Video animation, Review articles and research articles.
Teaching Methods (Forms of Teaching): Lectures, Presentation, Assignments, , ,
COURSE EVALUATION CRITERIA

Method Quantity Percentage (%)
Quiz 2 5
Homework 4 2.5
Midterm Exam 1 25
Presentation 1 10
Social media- community effecting post 1 5
Final Exam 1 40
Total 100
Examinations: Essay Questions, True-False, Multiple Choices, Short Answers, , ,
Extra Notes:
ECTS (ALLOCATED BASED ON STUDENT) WORKLOAD

Activities Quantity Workload Hours for 1 quantity* Total Workload
Theoretical Hours 16 3 48
Practical Hours 16 0 0
Final Exam 1 15 15
Quiz 2 3 6
Homework 4 3 12
Midterm Exam 1 6 6
Presentation 1 9 9
Social media- community effecting post 1 5 5
Total Workload 101
ECTS Credit (Total workload/25) 4

Peer review

Signature: Signature: Signature:
Name: Name: Name:
Lecturer Head of Department Dean